UK Commercial Clinical Research Model Agreements Have been revised

NHS 30 July 2025

0 JULY 2025 - The commercial model agreements for use with

parIcipaIng NHS and HSC organisaIons have been updated

(including the model non-intervenIonal study agreement -

mNISA) to align with the model Commercial Chief InvesIgator

Agreements published in June 2025 [Link].

RWR CONTEXT:

It is recommended that sponsors use the July 2025 versions of

these agreements in their IRAS submissions as soon as possible.

The July 2025 versions of the agreements will only be accepted

in new IRAS submissions from 1 October 2025. The May 2025

versions of the mNISAs, mC-PICA and the model Commercial

Hub and Spoke Agreement will not be accepted in new IRAS

submissions aeer 30 September 2025.

Link to website: https://www.hra.nhs.uk/about-us/news-updates/further-updates-to-the-commercial-agreements-for-participating-nhs-and-hsc-organisations/